Visualize What You Can Do with Imaging Mass Cytometry: Uncovering Spatial Biology

Thank you to our speakers and attendees at the October 2021 IMC Summit: Uncovering Spatial Biology. Throughout the meeting we saw how Imaging Mass Cytometry™ (IMC™) was used to markedly transform the investigation of the tissue microenvironment and decipher the complex secrets of spatial biology.

We hope you were inspired by the expert users and leaders in the Imaging Mass Cytometry community who shared their current research, tips and insights gained using IMC.

To tap into the wealth of information from this meeting, just go to the agenda for links. Learn from the experience of other IMC users about how to apply this powerful technology to your work and discover data analysis solutions that can enhance your results.
See agenda and presentations

An Exciting Agenda

The 2021 IMC Summit agenda includes translational research presentations, a roundtable discussion from hands-on expert users, a panel discussion on getting started and several talks focused on data analysis. Peruse through the agenda below and click on links to see the sessions.

Or download the agenda to share with your colleagues.

If you have any questions, want to request a seminar or an FAS visit at your institution, or want a quote, please let us know.
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October was Breast Cancer Awareness Month

In honor of this month, three excellent presentations on this topic were included in the Making an impact in breast cancer research session that kicked off the day. Our speakers selected the charity Touch, The Black Breast Cancer Alliance™, which will receive a $3,000 donation from Fluidigm to support the great research aimed at combating this disease.

Learn more about this organization at touchbbca.org or on Twitter, @touchbbca.

Topics and Speakers
Welcome to the IMC Summit 2021
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» Welcome address

Chris Linthwaite
 

Chris Linthwaite
President and CEO, Fluidigm

Michelle Macpherson

Michelle Macpherson (Moderator)
Director of Product Management,
Imaging Mass Cytometry, Fluidigm

Making an impact in breast cancer research
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» Introduction

Bernd Bodenmiller

Bernd Bodenmiller, PhD
Dual Professor for Quantitative Medicine
University of Zurich and Institute for Molecular Health Sciences, ETH Zurich

 

» Capturing diversity in tumor microenvironments: Biological determinants of breast cancer disparities

Melissa Davis

Melissa Davis, PhD
Assistant Professor of Cell and Developmental Biology
Scientific Director of the International Center for the Study of Breast Cancer Subtypes, Weill Cornell Medicine

 

» Obesity, inflammation and cancer

Daniela Quail

Daniela Quail, PhD
Assistant Professor, Department of Physiology
Rosalind and Morris Goodman Cancer Research Centre, McGill University

IMC Summit Keynote Presentation
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» Using IMC to understand the neuroinflammation of severe COVID-19 infection

Bertram Bengsch

Bertram Bengsch, MD, PhD
Group Leader, Department of Internal Medicine II
University Medical Center Freiburg

Break
Visit The Promise of IMC and Product Kiosks
Ask an FAS
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» Sample preparation and panel design

Leigh-Anne McDuffus

Leigh-Anne McDuffus
Field Applications Specialist, Proteomics, Fluidigm

Expert User Insights: Roundtable Discussion
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» Roundtable discussion

Noah Saederup

Noah Saederup, PhD (Moderator)
Senior Product Manager, Mass Cytometry Reagents, Fluidigm

Dan Traum

Dan Traum (Panelist)
Research Specialist, University of Pennsylvania

 
Marieke E. Ijsselsteijn

Marieke E. Ijsselsteijn (Panelist)
PhD Candidate, Leiden University Medical Center

Anthony Colombo

Anthony Colombo (Panelist)
PhD Student in Biostatistics at University of Southern California, in collaboration with Cedars-Sinai Graduate School of Biomedical Sciences

Ask an FAS
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» ROI selection and considerations in selecting a data analysis pipeline

Eric Swanson

Eric Swanson, PhD
Senior Field Applications Specialist, Proteomics, Fluidigm

Introducing Maxpar® OnDemand Antibodies
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» Introducing Maxpar® OnDemand Antibodies

Clinton Hupple

Clinton Hupple
Product Manager, Proteomics, Fluidigm

2021 Publication Spotlights
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» The spatial landscape of lung pathology during COVID-19 progression

Andre Rendeiro

André Rendeiro, PhD
Postdoctoral Associate in Computational Biomedicine
Institute for Computational Biomedicine and Englander Institute for Precision Medicine, Weill Cornell Medicine

 

» Immunogenomics of colorectal cancer response to checkpoint blockade: Analysis of the KEYNOTE 177 trial and validation cohorts

Michele Bortolomeazzi

Michele Bortolomeazzi (Joint Speaker)
PhD Student, Cancer Research UK King’s Health Partners Centre
Cancer Systems Biology Group, King’s College London, Francis Crick Institute

Lucia Montorsi

Lucia Montorsi, PhD (Joint Speaker)
Assistant Professor, Department of Physiology
Rosalind and Morris Goodman Cancer Research Centre, McGill University

Ask an FAS
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» Getting the most out of your data analysis

Wendell Smith

Wendell Smith, PhD
Field Applications Specialist II, Proteomics, Fluidigm

Getting Started: Panel Discussion
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» Panel discussion

Michelle Macpherson

Michelle Macpherson (Moderator)
Director of Product Management,
Imaging Mass Cytometry, Fluidigm

Hiran Ravichandran

Hiran Ravichandran, MS (Panelist)
Research Associate, Weill Cornell Medicine

 
Aida Meghraoui-Kheddar

Aida Meghraoui-Kheddar, PhD, PharmD (Panelist)
Senior Postdoc, Institute of Molecular and Cellular Pharmacology

Corinne Ramos

Corinne Ramos, MBA, PhD (Panelist)
Innovation & Marketing Director, ImaBiotech

Ask an FAS
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» Dual-mode system use, calibration and other instrument operation

Ron Cohn

Ron Cohn, MS
Senior Field Applications Specialist, Proteomics, Fluidigm

Break
Data Analysis Session I: The importance of cell segmentation in the data analysis pipeline
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» Notes from the bench: IMC data analysis from a biologist’s perspective

Hartland Jackson

Hartland Jackson, PhD
Investigator, Lunenfeld-Tanenbaum Research Institute

 

» Imaging Mass Cytometry and single-cell segmentation of lung tissue samples

Jay Hirota

Jay Hirota, PhD (Joint Speaker)
Canada Research Chair in Respiratory Mucosal Immunology
Assistant Professor of Medicine, McMaster University

Kjetil Ask

Kjetil Ask, PhD (Joint Speaker)
Associate Professor, Firestone Institute for Respiratory Health
McMaster University

Data Analysis Session II: Visiopharm® high-multiplex software and a new import function
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» Build a strong foundation: Powerful cell segmentation with Visiopharm’s advanced phenotyping software

Brit Boehmer

Brit Boehmer, PhD
Technical Sales Specialist, Visiopharm

Data Analysis Session III: An operationalized pipeline with IF data merging, HALO® and ImaCytE
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» Integrating IMC into an initial QC and deep multi-omic phenotyping workflow: A tissue-sparing approach to maximize the amount of remaining clinically collected tissues for other spatial technologies

M. Caleb Marlin

M. Caleb Marlin, PhD
Project Manager, Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation

Data Analysis Session IV: Data analysis methods in emerging applications
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» Barcoded IMC assays for an efficient spatial profiling of 3D spheroids

Vito Zanotelli

Vito Zanotelli, PhD
Recently from the Bodenmiller Lab, Department of Quantitative Biomedicine, University of Zurich

 

For Research Use Only. Not for use in diagnostic procedures.

Limited Use Label License: The purchase of this Fluidigm Instrument and/or Consumable product conveys to the purchaser the limited, nontransferable right to use with only Fluidigm Consumables and/or Instruments respectively except as approved in writing by Fluidigm: www.fluidigm.com/legal/salesterms. Patents: fluidigm.com/legal/notices. Trademarks: Fluidigm, the Fluidigm logo, Imaging Mass Cytometry, IMC and Maxpar are trademarks and/or registered trademarks of Fluidigm Corporation or its affiliates in the United States and/or other countries. All other trademarks are the sole property of their respective owners. ©2021 Fluidigm Corporation. 11/2021