December 7, 2021
Emerging Approaches to Improving Adoptive Cell Therapy
This mini-symposium brought together investigators taking innovative approaches to address these challenges. The expert research presented will span diverse aspects of CAR cell therapeutic development, from expanding our understanding of immune cell function to improving CAR T manufacturing to monitoring CAR cells in clinical research trials.
A moderated panel discussion allowed the audience members to interact with the speakers for Q&A.
Watch the on demand recording by following the link below.
Flyer on mass cytometry for CAR cell analysis: A Streamlined Research Assay for Longitudinal Immune Monitoring of Cellular Therapies
|Topics and Speakers|
» Expanding CAR T cell profiling to accelerate therapeutic insights
» Understanding the metabolic dynamics of T cells and CAR T cells from single-cell data
Matthew Spitzer, PhD
» Introducing CyTOF® XT and Maxpar™ Direct™ Assays for efficient high-content immune profiling
Emily Thrash, PhD
» Mass cytometry: A robust platform for the comprehensive immunomonitoring of CAR T cell therapies
Jonathan Caron, PhD
» Interrogating CAR T cell spatiotemporal plasticity
Lior Goldberg, MD
- Corneau, A. et al. “Mass cytometry: a robust platform for the comprehensive immunomonitoring of CAR-T-cell therapies.” British Journal of Haematology 194 (2021): 788–792.
- Levine, L.S. et al. “Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response.” Immunity 54 (2021): 829–844.e5.