1000 Reasons to CyTOF. Celebrating over 1,000 published discoveries-and counting!

Don’t just research. CyTOF.

The art of single-cell analysis transformed into a precise science

Mass cytometry, powered by CyTOF^® technology, is the most capable and proven system available for high-parameter cytometry. Vetted by more than 1,000 publications, mass cytometry has helped unveil new cell types, functions and biomarkers in cancer, autoimmunity, immunology and many other research areas.

With CyTOF you can:

Bring the precision of mass spectrometry to your single-cell analysis.
Measure more than 50 parameters per cell in only a single tube of sample.
Upgrade your cytometry capabilities—it’s more affordable than ever!

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Make the switch to CyTOF simple with our Flow Cytometer Trade-In Program.

Hear from a core facility director on the CyTOF advantage

A head-to-head comparison of cost and workflow for flow and mass cytometry

Matt Cochran, MS
Technical Director,
University of Rochester Medical Center Flow Cytometry Shared Resource

Lose the spillover and start speaking CyTOF

Mass cytometry uses heavy metal isotope tags to label cellular targets for precise detection in 135 distinct channels. This powerful system results in negligible background signals and minimal signal overlap.

For the cytometry user this means:

No unmixing or deconvoluting data prior to analysis
No autofluorescence or spectral overlap to account for
No tray full of control tubes required for your experiment
You can build and expand panels in days, not weeks.
A once-a-day calibration gets you ready to run any assay you choose.

See the difference in your data

With mass cytometry, what you see is what you get.

Easily interrogate more than 20 markers simultaneously on millions of individual cells without having to compromise sensitivity or accuracy due to signal compensation or spectral unmixing. No spreading error to fear—whether you want to look at 20 markers or more than 50.

Mass cytometry adoption is rising quickly.

Here’s why:

CyTOF panels are easier to build and modify than those for high-dimensional fluorescence cytometry.
A single mass cytometry panel can replace multiple flow cytometry panels, using far less precious sample and reagents per experiment.
Mass cytometry antibodies and tags are more robust and stable than fluorescent tags. Cocktails and labeled cells can be frozen.
Run your entire experiment in a single tube by multiplexing samples with barcoding.

Benefit from the broadest range of applications for both basic and translational research.
- Phenotyping by cell surface or intracellular markers
- Cytokine production
- Cell death and apoptosis
- Signaling and transcriptional protein analysis
- Cell cycle analysis
- T cell receptor identification with tetramer technology
- Epigenetic studies

Areas of study

Don’t sell your research short

Mass cytometry is now more affordable than ever

Reduce your cost in time, sample and reagents.
Shorten your time to result: Build and validate panels in days, not months.
Take advantage of highly competitive systems pricing.
Our Flow Cytometry Trade-In Program lets you easily make the switch to mass cytometry.

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July 2020 issue of Mass Cytometry Trending Now

A brief anthology of recent papers using mass cytometry in COVID-19 disease research studies

Download

Experience cytometry without limits

Investigate both phenotype and function at the same time:
- Signaling networks (phosphoproteins)
- Transcription factors
- Cell cycle analysis
- Post-translational modifications

All cells are welcome: PBMC, whole blood, tissue and tumor digests.

Proven applications of mass cytometry include:
- Biomarker discovery
- Checkpoint inhibitor studies
- Tumor and tissue microenvironment
- Immune monitoring and profiling
- Engineered cell and antibody product development

Use an extensive selection of antibodies and panels

Fluidigm Maxpar® reagents for mass cytometry provide plenty of panel design flexibility. Build your own panel with our high-quality, directly conjugated antibodies to mouse and human epitopes. In a single afternoon, you can easily label antibodies of your choice with any of 42 isotopic metals. Or choose from one of 28 pre-designed panel kits that enable a wide range of applications.

Whatever you decide, our Field Application Specialists are ready to help you design your first panel.

Ask for a free panel-building consultation today

Maxpar Direct Immune Profiling System

The first complete sample-to-answer solution for high-dimensional immune profiling, the Maxpar® Direct™ Immune Profiling System brings together CyTOF technology on the Helios™ system, a dry 30-marker antibody panel and automated Maxpar Pathsetter™ software, so you can easily count 37 immune cell populations in human PBMC and whole blood.

30 unique markers, 1 sample tube

5-minute data analysis

37 immune cell populations quantified

Easy workflow
Customizable and expandable panel
Fast sample-to-answer
Freeze and ship samples.
No special expertise required for data analysis

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