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1000 Reasons to CyTOF. Single-tube cytometry is more published and affordable than ever.
1000 Reasons to CyTOF. Single-tube cytometry is more published and affordable than ever.

Break through without breaking the bank.

Mass cytometry is simpler and more cost-effective than you may think. This single-cell analysis instrument was designed to help you harness the power of less: less hassle, less time spent on experiment prep and fewer tubes—saving you money and time in the long run.

CyTOF® technology makes single-tube cytometry possible, providing the most capable, proven and easy-to-use system for high-parameter cytometry.

Vetted by more than 1,000 publications, CyTOF has helped our partners unveil new cell types, functions and biomarkers in cancer, autoimmunity, immunology and many other research areas.

  • Upgrade with ease. New pricing fits CyTOF into your budget.
  • Experience precision. Bring the accuracy of mass cytometry to your single-cell analysis.
  • Elevate, don’t complicate. Measure more than 50 parameters per cell in a single sample tube.
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Hear from a core facility director on the CyTOF advantage.

A head-to-head comparison of cost and workflow for flow and mass cytometry

Matt Cochran, MS
Technical Director,
University of Rochester Medical Center Flow Cytometry Shared Resource

Lose the spillover and start speaking CyTOF.

Mass cytometry uses heavy metal isotope tags to label cellular targets for precise detection in 135 distinct channels. This powerful system results in negligible background signals and minimal signal overlap.

For the cytometry user this means:

  • No unmixing or deconvoluting data prior to analysis
  • No autofluorescence or spectral overlap to account for
  • No tray full of control tubes required for your experiment
  • You can build and expand panels in days, not weeks.
  • A once-a-day calibration gets you ready to run any assay you choose.
  

See the difference in your data.

With mass cytometry, what you see is what you get.

Easily interrogate more than 20 markers simultaneously on millions of individual cells without having to compromise sensitivity or accuracy due to signal compensation or spectral unmixing. No spreading error to fear—whether you want to look at 20 markers or more than 50.

Mass cytometry adoption is rising quickly.

 

Here’s why:

  • CyTOF panels are easier to build and modify than those for high-dimensional fluorescence cytometry.
  • A single mass cytometry panel can replace multiple flow cytometry panels, using far less precious sample and reagents per experiment.
  • Mass cytometry antibodies and tags are more robust and stable than fluorescent tags. Cocktails and labeled cells can be frozen.
  • Run your entire experiment in a single tube by multiplexing samples with barcoding.
  • Benefit from the broadest range of applications for both basic and translational research.
    • Phenotyping by cell surface or intracellular markers
    • Cytokine production
    • Cell death and apoptosis
    • Signaling and transcriptional protein analysis
    • Cell cycle analysis
    • T cell receptor identification with tetramer technology
    • Epigenetic studies
 

Areas of study

Don’t sell your research short.

Mass cytometry is now more affordable than ever

  • Reduce your cost in time, sample and reagents.
  • Shorten your time to result: Build and validate panels in days, not months.
  • Take advantage of highly competitive systems pricing.
  • Our Flow Cytometry Trade-In Program lets you easily make the switch to mass cytometry.
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July 2020 issue of Mass Cytometry Trending Now

A brief anthology of recent papers using mass cytometry in COVID-19 disease research studies

Download

Experience cytometry without limits

  • Investigate both phenotype and function at the same time:
    • Signaling networks (phosphoproteins)
    • Transcription factors
    • Cell cycle analysis
    • Post-translational modifications

  • All cells are welcome: PBMC, whole blood, tissue and tumor digests.  

  • Proven applications of mass cytometry include:
    • Biomarker discovery
    • Checkpoint inhibitor studies
    • Tumor and tissue microenvironment
    • Immune monitoring and profiling
    • Engineered cell and antibody product development

Use an extensive selection of antibodies and panels.

Fluidigm Maxpar® reagents for mass cytometry provide plenty of panel design flexibility. Build your own panel with our high-quality, directly conjugated antibodies to mouse and human epitopes. In a single afternoon, you can easily label antibodies of your choice with any of 42 isotopic metals. Or choose from one of 28 pre-designed panel kits that enable a wide range of applications.

Whatever you decide, our Field Application Specialists are ready to help you design your first panel.

Ask for a free panel-building consultation today

Maxpar Direct Immune Profiling System

The first complete sample-to-answer solution for high-dimensional immune profiling, the Maxpar® Direct™ Immune Profiling System brings together CyTOF technology on the Helios™ system, a dry 30-marker antibody panel and automated Maxpar Pathsetter™ software, so you can easily count 37 immune cell populations in human PBMC and whole blood.

 

30 unique markers, 1 sample tube

 
 

5-minute data analysis

 
 

37 immune cell populations quantified

 
  • Easy workflow
  • Customizable and expandable panel
  • Fast sample-to-answer
  • Freeze and ship samples.
  • No special expertise required for data analysis
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Hello! We are confident you will be just as excited as we are about CyTOF XT. 

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Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.