Simplify your high-parameter cytometry and accelerate your single-cell profiling studies.
Simplify the design and execution of deep cell profiling studies.
Standardize sample analysis with reproducible workflows and automation.
Accelerate novel therapeutic research to improve human health outcomes.
Ignite your research.
CyTOF XT™ is the most technologically advanced mass cytometer to date, designed to build on the benefits of CyTOF technology while simplifying operation and automating sample acquisition for the best reproducibility and time to results from every run.
XTra Autonomy
Walk away from sample loading, acquisition and monitoring. Do more with your time.
XTra Efficiency
With easy setup and automated system optimization, enjoy peak performance from minimal effort.
XTra Clarity
Achieve unrivaled quality and depth of understanding from a greater selection of markers.
XTra Insight
Simplify cell profiling with standardized workflows to accelerate therapeutic development.
Take a closer look at the CyTOF XT.
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With all these XTra benefits, imagine what insights await you next.
CyTOF Technology
Powered by mass spectrometry and CyTOF technology, mass cytometry elevates cell analysis with a level of speed, precision and reproducibility not enabled by other single-cell platforms.
CyTOF XT further enhances the capabilities of mass cytometry with workflow automation that simplifies sample processing and data acquisition.
The instrument offers a new level of autonomy through streamlined operation, automatic monitoring and easier system management. The result is superior data quality—so you can focus on what matters most.
XTra Autonomy
CyTOF XT automation expands what your lab can accomplish by simplifying daily workflows and freeing operator time for other tasks.
Chilled sample carousel
Cools to 4–8 °C
Holds twelve 5 mL and one 15 mL sample tube
Walk-away sample acquisition
Acquire up to 13 different samples and panels in a single batch run.
Automated resuspension of sample pellets and addition of normalization beads.
Automated clog sensing
Software and hardware innovations provide internal fluidics monitoring of clog formation.
An unclogging routine is automatically activated by the fluidics system.
XTra Efficiency
Simplified front-end assembly, bottle tray for solutions and automated tuning minimize maintenance and calibration.
Easy daily setup
High-capacity solution reservoirs need attention only once a week.
Daily instrument cleaning takes just minutes.
Automated system tuning
Only a single daily optimization with EQ™ Calibration Beads is required.
No additional system adjustments or optimization is needed for any panel or sample type.
Real-time signal optimization
Detector voltage adjusts automatically to maintain optimal signal detection during extended acquisitions.
XTra Clarity
The precision of measuring marker expression using mass cytometry is unmatched by fluorescence cytometry methods. Cleaner signals mean data is more accurate.
Unrivaled data quality
Minimal to no background signal is seen in detection channels.
No signal compensation or deconvolution is required after data collection.
On-the-fly data normalization
Most cytometric markers
Multiple 50-plus-marker panels have been published.
Panels of 40 or more markers are common: Over 100 examples are peer-reviewed and published.
Superior cell profiling
CyTOF enables the broadest range of high-parameter cytometry applications.
Easily incorporate sample barcoding
Publications and clinical research trials
The broad adoption of mass cytometry for basic, translational and clinical research has driven a rapidly growing bibliography of peer-reviewed publications and use in clinical research trials. See the List.
Over 1,200 peer-reviewed publications as of March 31, 2021
As of April 2021, over 150 ongoing or completed National Clinical Trials have reported use of mass cytometry.
Service and support
We’ve got you covered with Fluidigm PRO Services.
A critical success factor when adopting high-performance technology is acquiring the proficiency and support to accelerate your research and discovery initiatives. Fluidigm PRO Services are a comprehensive portfolio of solutions to help you maximize your investment, scale up productivity and empower your laboratory with greater access to professional resources.
Learn more about our integrated approach to supporting your laboratory.
Service Plans
Maximize your investment and system performance.
Explore our comprehensive and flexible service coverage options to keep your system operating at peak productivity.
Compliance Services
Support your quality management system.
Our qualification services help maintain your instrument compliance requirements and optimize system performance.
Learn more about key CyTOF XT features including fully automated acquisition with clog sensing and new data processing, making CyTOF XT the most affordable and flexible high parameter cytometer.